bacterial and host-derived glutathione are required to activate prfa

bacterial and host-derived glutathione are required to activate prfa Multiple regulatory check-points control expression protein Glutathione metabolism impacts fungal virulence

Name: bacterial and host-derived glutathione are required to activate prfa Multiple regulatory check-points control expression protein Glutathione metabolism impacts fungal virulence
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Glutathione metabolism impacts fungal virulence by modulating the redox environment bioRxiv Diverse roles of low molecular weight thiol GSH in Francisella's virulence, location sensing and GSH stealing from host ScienceDirect Allosteric GSH binding primes PrfA for DNA binding. (A and B) Download Scientific Diagram Listeria monocytogenes regulates PrfA activity so as to increase Download Scientific Diagram

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Consistent with the transcriptome analysis, qRT-PCR also showed that expression of defense marker genes ( CYP94C1 , JAZ13 , LOX4 , OPR3 , JAZ5 , JAZ7 , and JAZ10 ) was highly induced in the systemic leaf tissues of GSH-treated plants (Fig