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Mast cell chymase impairs bronchial epithelium integrity by degrading cell junction molecules of epithelial cells

41 Also of note, occludin-null mice were born in expected Mendelian ratios with no gross phenotype, although they did show significant postnatal growth retardation

This strategy modulates tumor cell death pathways via externally applied thermal stress and, when integrated with tumor-specific metabolic reprogramming, facilitates a controlled shift from ferroptotic to non-ferroptotic cell death