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In addition to a potentially direct antioxidant activity, curcumin can induce the expression of phase II antioxidant enzymes, including glutamate-cysteine ligase (GCL), the rate-limiting enzyme in glutathione synthesis

Age-Related Decline and the Anti-Aging Question The 60% decline in plasma GHK-Cu from age 20 to 60 has prompted speculation that GHK-Cu supplementation could slow or partially reverse aspects of biological aging

This characteristic makes cardiac glycosides good candidates as senolytics to target senescent cells, due to their role as specific inhibitors of the NA + /K + ATPase pump