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BMP activation drives hepatic bias in GPX2-deficient PFG To elucidate the molecular basis of the PFG differentiation bias observed in KO cells, we leveraged RNA-seq and scRNA-seq datasets to analyze differential signaling pathway activity across key developmental stages: PFG, PEN, and SC- cell

Cirelli Mediators of Inflammation.2020

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Persistent TCM Methodological Hurdles: Inherent complexities in TCM research, including unclear bioactive components, poorly understood multi-component synergistic mechanisms, and challenges in ensuring reliable experimental interventions and placebo controls, continue to pose substantial obstacles, raising concerns about the reproducibility of findings and hindering mechanistic understanding