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Natural compounds, such as L-carnitine, with antioxidant, anti-inflammatory, and lipid-modulating properties, are being explored as potential supplements to prevent and treat chronic diseases

Zinc Zinc, like iron, is involved in thyroid homeostasis, contributing to thyroid hormone synthesis and action at various levels: modulating TRH and TSH synthesis at the hypothalamic-pituitary level

Apomorphine, a recently FDA-appro ved, short-acting, dopamine agonist, is delivered by subcutaneous injection as a rescue dose to manage the sudden and refractory motor fluctuations of L-dopainduced "off" periods in patients with PD

An MTHFR variant does not directly measure current SAM, SAH, methylation capacity, oxidative stress, glutathione status or mitochondrial function