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10.3390/ijms20010004 84 Iwata-IchikawaE.KondoY.MiyazakiI.AsanumaM.OgawaN

Whereas the riboflavin biosynthesis pathway is most extensively studied in Bacillus subtilis 32 and Escherichia coli 33 , which can reside in the gut at different levels, one systematic genome assessment has found that each of the eight B vitamins (B1, B2, B3, B5, B6, B7, B9, and B12) can theoretically be produced by 4065% of the 256 studied human gut strains 34

It is a possibility that the inconsistent effects of yellow maca on fertility may be due to its preparation, size of the hypocotyl, type of extract (e.g., aqueous or methanolic extract), fractions from the extract (e.g., butanolic or aqueous), pH of the extract, and mode of administration [34,197]