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10.1142/S0192415X2550020X 43 ZhangY.TianX.ZhangK.ZhaoK.WangY.MaC.et al (2024)

The poor responsiveness to antidepressant therapy of the UM phenotype also clinically correlates with a higher incidence of suicides relative to that of deaths due to natural causes in this patient population

In contrast, the levels of calcium channel-related proteins Mitochondrial Calcium Uniporter (MCU), Sodium Calcium Lithium Exchanger (NCLX), and Leucine Zipper and EF-Hand Containing Transmembrane Protein 1 (LETM1) were reduced only in PACS patients with neuropsychiatric symptoms