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For pernicious anaemia or malabsorption, intramuscular hydroxocobalamin is the NHS standard treatment, with an initial loading regimen followed by maintenance injections every 2-3 months

Diabetes Foot Care Between 50% and 75% of lower extremity amputations occur in individuals with diabetes, with over 50% of these amputations being preventable through proper foot care

While Vitamin B12 tablets (cyanocobalamin) can be helpful for mild deficiencies or maintenance, they are not as effective as injections for correcting severe deficiencies

PARPs, on the other hand, respond to DNA damage by using NAD + to generate ADP-ribose polymers, which are essential for DNA repair and maintaining genome stability