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10.1164/rccm.202403-0636OC 64 LiC.LuY.DuS.LiS.ZhangY.LiuF.et al (2017a)

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It works by blocking the overactive immune signalsspecifically the JAK-STAT pathwaythat lead to follicular inflammation and hair loss

Treatment with rapamycin disrupts the interaction between YY1 and PGC-1, resulting in decreased expression of mitochondrial genes

Using the same visual field as that of the positive drug group, mice in the CaT-ME and CaT groups exhibited significant increases in the number of hair follicles when compared to the control group, and the hair grew down to the subcutaneous tissue