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Although VEGF-D is a potential biomarker for ramucirumab in colorectal and hepatocellular carcinoma, earlier studies did not identify it as a useful biomarker for patients with GC (156)

For example, one of the key insights in systems basal ganglia research within the last decades was the finding that the basal ganglia, thalamus, and cerebral cortex are components of anatomical circuits with separate territories in the individual anatomical nodes of the networks for motor, associative, and limbic functions [42, 43]

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