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Oxid Med Cell Longev (2014) 2014:360438

Post-transplant cyclophosphamide for the prevention of graft-vs.-host disease in allogeneic hematopoietic cell transplantation: A guide to management for the advanced practitioner

The authors hypothesize that the enzyme uptake may be hindered by physical barriers in the tissue since cells that are of easier access to the enzyme, such as endothelial cells, have their deposits cleared