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Univariate statistical testing using two-sample t-tests with confirmation by Wilcoxon rank-sum tests identified four metabolitescoumarin, L-leucine, L-octanoylcarnitine, and kaempferolthat differed significantly between ASD and control groups after FDR correction, with large effect sizes (Supplementary Table S2)

526 Recently, several combination therapies have been developed that, rather than targeting mTOR directly, focus on its upstream regulators in conjunction with immunotherapy

1 Selenoproteins contain the 21 st amino acid selenocysteine, which differs from cysteine by a single atom, selenium replacing for sulfur

oleifera leaves, including two newly discovered alkaloids, marumoside A and B, and aurnatiamide acetate isolated from the roots [42,46]