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doi: 10.1021/acs.jafc.0c05240 66 LiXLuZQiYChenBLiB

Amino acids are the fundamental components of proteins and are necessary in many internal functions of the body

One of the intermediates in the formation of kyn from tryptophan metabolism, N-formyl-kynurenine (NFK), differs from other tryptophan metabolites in its photophysical properties, in that it acts as a photosensitiser to produce singlet oxygen and superoxide (103, 104)

Direct tissue temperature measurements suggested that therapeutic freezing may not have extended across the full diameter of the sciatic nerve, highlighting a key technical limitation that may explain the lack of clinical benefit