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** Patient 6 moved out of the area and did not complete the study

Using collagen hydroxylate during an initial phase of rehabilitation can be beneficial

Activation of aerobic glycolysis-related bypass pathways Increased glycolysis simultaneously activates multiple self-associated bypass pathways, among which the PPP provides the raw material for purine and pyrimidine nucleotide synthesis and maintains redox homeostasis for cancer cell growth, which largely depends on the activity of glucose-6-phosphate dehydrogenase (G6PD), as it catalyzes the first step of the glucose-6-phosphate shift to the PPP [46]