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Whereas initial studies suggest that its expression in the proximal tubules is very low, recent studies using microdissected, freshly-isolated, murine, nephronic segments demonstrated the highest IGF-1R mRNA expression in proximal tubules along the nephron [11]

and White, L.: SureSmile: A report of clinical findings, J

Data Extraction Extracted variables included study design, peptide agent and formulation, dosing regimen and route of administration when reported, musculoskeletal indication, comparator group, outcome measures, efficacy findings, and adverse events

11 WADA Prohibited ListIGF-1 and its analogs are prohibited substances in competitive sport (S2 peptide hormones / growth factors)