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Description

Mitochondrial GPX4 protects cardiac contractile function and preserves electron transport chain activities following ischemia/reperfusion [54]

Glucose-6-phosphate dehydrogenase (G6PD), which serves as a primary source of NADPH oxidase, a reducing agent, and a hydrogen ion donor in the reduction reaction, plays multiple roles in energy supply, signaling, and antioxidant reactions (Stanton, 2012