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What Your GSTM1 and GSTT1 Results Can and Cannot Tell You GSTM1 and GSTT1 deletion status reveals whether you carry functional copies of these genes whether the glutathione conjugation layer of estrogen quinone detoxification is present or absent at the enzymatic level

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This is primarily achieved through the activation of VDR signaling, which inhibits key pathways, such as NF-B, promotes a shift in macrophage polarization from the pro-inflammatory M1 to the anti-inflammatory M2 state, and directly suppresses HSC activation to reduce fibrosis