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Additionally, all three compounds increased antioxidant enzyme activity (SOD, APX and CAT), with melatonin showing the highest increases (25 %, 42.86 % and 31.5 %)

Nature (2014) 515(7527):4315

ALA supplementation might be useful in AD development because it can improve mitochondrial function in patients with AD by acting as a cofactor of the mitochondrial enzyme complex and antioxidant [127]