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Blood clots: It may promote the formation of blood clots , which are dangerous as they can block blood flow to vital organs such as the brain or heart

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Thus, TB-500 may be hypothesized to support angiogenesis by combining a cytoskeleton-linked increase in endothelial motility with signaling changes that raise pro-angiogenic programs (VEGF-A and Ang2/Tie2) via Notch/NF-B coupling in damaged cellular structure