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Whitening skin and dark spots

N Engl J Med 343 , 19021909 (2000)

In this section, we will elaborate upon the epigenetic modulations introduced by the Wnt pathway that promote cancer initiation as well as progression

The PI3K/PTEN/Akt/mTOR signaling pathway is deregulated in numerous cancers leading to altered cellular processes, which makes this axis an attractive target for therapeutic manipulations