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Ginseng Res

Beyond the previously outlined mechanisms of MNNG carcinogenesis, there are specific characteristics in the mechanism by which MNNG results in gastric adenocarcinoma

The amino acid glutathione is a naturally occurring protein already in your body

To further prove the influence of intracellular GSH level on the cytotoxicity of NSBSO, we pre-treated 4T1 and B16 cells with GSH synthesis inhibitor to reduce the intracellular GSH level, and the results showed that the pretreatment of the inhibitors gradually reduced the intracellular GSH to a very low level after 24 h treatment (Additional file 1: Fig