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the two groups had similar clinical features [ALT 5140 vs 2384 U/L], but chronic exposure cases were younger [mean age 3.5 vs 15 years], less likely female [46% vs 82%], and more likely to die [12% vs 2%], however only 22% of them were diagnosed as acetaminophen overdose [37% were "indeterminant"])

Medical implications of melatonin: receptor-mediated and receptor-independent actions

When an abnormal form of an enzyme causes pathology it is referred to as an enzymopathy

Generation of PI3KC2B KO and heterozygous mice showed that the mutation did not cause any morphological aberrations in the affected neurons, nor did it result in any prominent cortical dyslamination