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Astrocytes and amyotrophic lateral sclerosis/motor neuron diseases Motor neurons are damaged by oxidative stress and reactive astrogliosis in ALS patients (Rao and Weiss, 2004

, 9 on the other hand, found no differences in the activities of CuZn-SOD, CAT and GPx between SHR and age-matched 6-month-old WKY rats, but found some discordance in Mn-SOD, CuZn-SOD, CAT and GPx protein levels in the medulla and cortex of SHR