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Besides, consistently higher paracetamol regimen may minimize all problems related to possible variations from animal to animal and from time to time in a given animal and invariably link paracetamol action with seizures, severely damaged brain tissue, hepatomegaly, fatty liver and necrosis, breakdown of liver function with profoundly increased ammonia, AST and ALT levels

2002 Aug;23(4):365-8

If you use sterile water, you can only draw from the vial once before contamination becomes a risk