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Similar content being viewed by others Introduction In the past decade, immunotherapy has emerged as one of the most promising cancer treatment strategies 1,2,3,4

In summary, metformin induces UCP2 overexpression in adipocytes, potentially minimizing oxidative stress due to drug-induced respiratory inhibition (Table 1)

Following, the complex enters the nucleus, where it binds to another transcriptional factor and to the DNA producing induction and gene rebuke, what finally leads to its anti-inflammatory, immunosuppressant and mineral corticoid effect

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