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The localization of these plant enzymes can be investigated using techniques such as localized gene expression studies, cell fractionation, Western blot analysis, immunolocalization with electron microscopy, fusion with fluorescent proteins, as well as transcriptomics and proteomics of cellular compartments (Parish, 1971

Thus, the major metabolites of paracetamol at the therapeutic dose level are: paracetamol sulfate, paracetamol glucuronide, paracetamol L-cysteinyl conjugate [more exactly 3-(L-cysteinyl)-4-acetamidophenol] (PLCC) and paracetamol N-acetyl-L-cysteinyl conjugate [more exactly 3-(N-acetyl-L-cysteinyl)-4-acetamidophenol] (PNALCC) (Nicholls et al ., 1997)

ACS Nano 4, 74517458