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While patients do often see a flare-up in acne breakouts when they first begin taking Accutane, these breakouts should clear up within the first few weeks of treatment, and patients will continue to see improvement throughout the time theyre taking isotretinoin

have received support from the McCormick and Gabilan Faculty Fellowship Award (SPO 272363) and the National Institutes of Health (NIH 1R01DK134989)

Start with lower concentrations and gradually increase as skin tolerance develops

doi: 10.3389/fpsyt.2014.00048 [DOI] [PMC free article] [PubMed] [Google Scholar] 11.Szcs A, van der Lubbe SCC, Arias de la Torre J, Valderas JM, Hay SI, Bisignano C, et al