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Within the latter family, two primary receptors are of paramount importance: RIG-I, which recognizes 5-triphosphorylated or diphosphorylated single-stranded RNA (ssRNA) and acts as the main cytosolic RNA sensor [215, 216], and MDA5, which recognizes viral RNA replicating in the cytoplasm [217, 218]

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Increased fruit and vegetable intake, especially to levels higher than 500 grams per day, has been linked to positive modification of GST polymorphisms that bring the GST activity closer to normal levels and improve antioxidant parameters

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And while some companies, such as Lilly, are testing their analogs as stand-alone therapies, others, including Novo Nordisk, are combining them with GLP-1s

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