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Symptoms of OIH include (but may not be limited to) increased levels of pain upon opioid dosage increase, decreased levels of pain upon opioid dosage decrease, or pain from ordinarily non-painful stimuli (allodynia)

In all cases, the ME/CFS patients were worse off than the long-COVID patients leading the authors to suggest that long COVID was an intermediate condition between health and ME/CFS

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There seems to be little if any cons to a collagen diet (excluding supplements)