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The peptide's primary function may not ultimately be sleep at all, although it is most closely associated with sleep cycle regulation, because DSIP levels are the same in CNS tissues as in peripheral tissues, suggesting that the peptide may also be formed outside the CNS

This makes it highly effective in managing peripheral neuropathy , including diabetic neuropathy, where it helps relieve numbness, tingling, burning sensations, and nerve pain

15 mg/kg was used in the VA Cooperative trial, so this dose is supported by evidence among patients who are not intubated