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However, comprehensive clinical studies including the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) and European First-Episode Schizophrenia Trial (EUFEST), revealed no clear advantages of atypical over typical drugs in terms of efficacy ( Figure 3 Antipsychotic-Induced EPS Clinical Symptoms Major EPS symptoms associated with antipsychotic treatment of BPSD include Parkinsonian symptoms, akathisia, and dystonia

In the pathogenesis of liver failure, enterogenous endotoxin can cause inflammatory cells to secrete TNF-, further damaging the liver cells

(b) impaired MFO and MGO

Overexpression of HSP70 in mice with mutant FUS protein is accompanied by a mitigated neurodegeneration in limbic system