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What are the first signs of B12 deficiency from nitrous oxide use

Ongoing research is exploring its potential benefits in preventing dementia, muscle atrophy, and kidney disease

After the addition of 25.0 ml oxalic acid VS (0.05 mol/l), the resultant mixture is heated to 80 C and titrated with potassium permanganate (0.1 mol/l), equivalent to 3.45 mg sodium nitrite