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Key Mechanistic Differences# Dosing Comparison# CagriSema Dosing# CagriSema is administered as a once-weekly subcutaneous injection at a target fixed dose of 2.4 mg cagrilintide + 2.4 mg semaglutide

The REZ includes the transition zone (or Obersteiner-Redlich zone), the site where central myelin (synthesised by oligodendrocytes) changes to peripheral myelin (synthesised by Schwann cells)