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Cancer-associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF-B activation

The cytokines IL-1, IL-6, IL-13 and IL-22 have been demonstrated to alter intestinal transcription of CLDN2 [27,28,29,30], although the impact this has on subsequent pore pathway permeability has not been fully elucidated