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That is a real risk arguably a greater one than the theoretical risks the FDA cited when it enacted the 2023 restrictions

*Correspondence: Weina Li, [email protected] Meng Li, [email protected] These authors have contributed equally to this work This article was submitted to Drug Metabolism and Transport, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

[1] It is not recommended in people with angle-closure glaucoma or bowel obstruction

Human trials are small and inconsistent Robust human clinical trials on injectable peptides for knee healing are limited