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Cell death modes: types and regulatory mechanisms The most common pathological change in heat stress-induced liver injury is massive degeneration and abnormal death of hepatocytes

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FABP1 /lysosomal-autophagy Fatty acid-binding protein 1 (FABP1), a liver-specific protein critical for intracellular lipid metabolism in the liver, has been shown in studies to enhance fatty acid uptake in hepatocytes when overexpressed, while its knockdown blocks lipid accumulation in these cells [85]