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Description

The P72R SNP has previously been described as differentially impacting somatically mutated p53 proteins on a functional and potentially structural level [15,16,17,18]

Besides, to maintain the homeostasis of nutrient intake, some patients will require an oral nutrition supplement (ONS)

However, antioxidant systems may be sensitive to NH 4 + feeding, which may again be associated with the oxidative damage due to ammonium toxicity [67,135]

Watanabe H, Hattori T, Kume A, Misu K, Ito T, Koike Y et al (2020) Improved Parkinsons disease motor score in a single-arm open-label trial of febuxostat and inosine