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Prior to experiments, cells were seeded in human plasma-like media (HPLM) containing 10% FBS and 1% penicillinstreptomycin

In line with this observation, recent studies showed that increasing expression levels of apoE3 or apoE4 in mutant hAPP or hAPP/PS1 transgenic mice actually increased amyloid deposition in their brains, suggesting that reducing, rather than increasing, apoE expression could be a promising approach to lowering brain A levels and decreasing plaque loads (Bien-Ly et al., 2012

In a study by Tang M et al., the blastocyst formation rate was significantly greater in fertilised eggs from old and young mice that underwent PNT (74.6% and 69.2%, respectively, P G mutant Leigh syndrome via MST, live-born neonates maintained 2.369.23% mtDNA mutation carriers across all tissues [135]

Several studies confirm that AgNPs preferentially accumulate on the surface of Gram-negative bacteria due to LPS, increasing their antimicrobial susceptibility (Pal et al., 2007)