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Its effects stay focused on adipose tissue: AOD9604 stimulates lipolysis primarily through beta3 adrenergic receptor pathways in adipose tissue, driving the breakdown of stored triglycerides into free fatty acids

Foci formation of P53-binding protein 1 in thyroid tumors: activation of genomic instability during thyroid carcinogenesis

Furthermore, a selective reduction in brain glutamine is also observed during SSADH deficiency (Gibson et al

The mRNA expression of SERCA (Sarco/ER Ca 2+ -ATPase for influx) and IP3R (inositol trisphosphate (IP3) receptor for efflux) was also examined, revealing a decrease in SERCA (the target of thapsigargin (TG)) and an increase in the most prominent isoform, ITPR3 (Supplementary Figure S11e and S11f)