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Kupffer cell activation Kupffer cells are the resident macrophages of the liver and regulate the inflammatory response within the liver

One older study found that high-dose intravenous glutathione was the most effective delivery method for people with fatty liver disease, and it significantly improved liver function tests several months after treatment

It is confirmed in endothelial cells that LPS induces ER stress and overproduction of IL-6 and MCP-1 through IRE1/NF-B pathway, resulting in endothelial dysfunction (124)

As Fer-1 and erastin were used as controls in subsequent experiments, the optimal concentrations of these reagents were also tested