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Mitochondria-targeted peptide prevents mitochondrial depolarization and apoptosis induced by tert-butyl hydroperoxide in neuronal cell lines

Knopp RC, Erickson MA, Rhea EM et al (2023) Cellular senescence and the bloodbrain barrier: implications for aging and age-related diseases

Another factor in treatment resistance involves the inhibitors of apoptosis proteins (IAPs), particularly X-linked IAP (XIAP), which shows the strongest anti-death effects through its ability to block caspase-9 activation [39]

however, there were increases in fasting glucose and HOMA-IR in the aspartame-exposed groups, and these were strongly related to the amount of ingested aspartame ( r = 0.518, P = 0.006)