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In case of a darker complexion or an uneven skin, there is also an elevated production of Eumelanin (a pigment responsible for imparting the dark brown color)

In addition to aging, ovarian reserve may be decreased due to ovarian surgery, chemotherapy, radiation therapy, and certain genetic factors

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Song Q, Chen Y, Wang J, Hao L, Huang C, Griffiths A, Sun Z, Zhou Z, Song Z (2020b) ER stress-induced upregulation of NNMT contributes to alcohol-related fatty liver development