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469,470 SIRT3 overexpression enhances SOD2 activity, lowering ROS, 471 and suppresses fibrosis pathways such as the TGF-/Smad pathway

Go to the Emergency Department If You Experience: Severe Dehydration Signs: Little to no urination Dry mouth and severe thirst Dizziness when standing Rapid heartbeat Sunken eyes Dangerous Symptoms: Bloody diarrhea or black, tarry stools High fever over 101.5F Persistent vomiting preventing fluid intake Severe abdominal pain Neurological symptoms (blurred vision, muscle weakness, difficulty speaking) Symptoms lasting more than 3 days High-Risk Groups Need Immediate Care: Pregnant Women: Call immediately if you have fever and flu-like symptoms

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