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(Van Antwerp et al, 1996

For example, ACSL4 preferentially showed high expression in ER-negative BC cell lines, such as human breast cancer cells (MDA-MB-231), but low expression in ER-positive BC cell lines, such as breast epithelial cells (MCF-7)

As it oxidizes, a noncovalently bound FAD is reduced, and electrons are transferred to coenzyme Q, contributing to the electron transport chain and ATP production