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doi: 10.1007/s12602-022-09909-5 27 BaiX.ZhuM.HeY.WangT.TianD.ShuJ

Methods: Tamoxifen-resistant cell lines previously developed and characterized in our laboratory were metabolically profiled with nuclear magnetic resonance spectroscopy (NMR) using cryogenic probe, and the findings were correlated with the expression of genes that encode the key enzymes of the significant metabolites

Briefly, the fixed-effect meta-analysis estimates were derived using Inverse Variance Weighting (IVW) in which the estimates from each replicate were weighted by the inverse of their variance estimates

At a higher dose of fluconazole 200 mg, incremental S-CIT dose adjustment by 25% did not yield the doses that satisfy the equivalent S-CIT exposure for G-EM and G-IM