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27 5 Polycystic Ovary Syndrome Causes & Risk Factors While the underlying cause of PCOS is unknown, abnormal insulin and hormone secretion and signaling appear to be key factors

The follow-up duration and hard endpoints are also insufficient: the median duration in phase III studies is 48 weeks, with no data on 2 years of mucosal maintenance or surgical rates, and the inclusion rate of hard endpoints is less than 10%

It is considered the master because it has the ability to regenerate other antioxidants, like Vitamin C and E