Nuclear Factor kappa-light-chain-enhancer of activated B cells (NF-kB) is a complex of transcription factors responsible for expression of many inflammatory genes
During these ten years, Arnold Schwarzenegger had already inspired future champions
After a marked decline in the mid-twentieth century, incidence has risen again over the last two decades, notably in high-income countries, reshaping the daily landscape of infectious neurology and reviving the clinical relevance of neurosyphilis as the great imitator ( Autoimmune encephalitis is now a well-defined, treatable cause of subacute neuropsychiatric syndromes, supported by consensus diagnostic criteria that have sharpened clinical recognition and encouraged early immunotherapy when appropriate ( Against this backdrop, a small but increasingly cited body of reports has described neurosyphilis presenting with a limbic encephalitis phenotype and, more provocatively, cases in which neurosyphilis coexists with neuronal surface antibodies, including anti-NMDAR antibodies ( Methods Because this phenomenon is uncommon and largely captured through case-based evidence, we performed a structured narrative review focused on publications describing neurosyphilis with a limbic encephalitis phenotype and publications reporting neuronal surface antibodies in the context of neurosyphilis
Also, issues related to the stability, bioavailability, and pharmacokinetics of supersulfide donors must be addressed to optimize their therapeutic efficacy and minimize potential side effects
