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CVD is the major macrovascular complication associated with T2DM, with two- to three-fold increased risk in T2DM individuals compared to non-diabetic population [12, 13], accounting for approximately 70% of global deaths among patients with T2DM [14, 15]

Disruption of Sel1L-HRD1 activity leads to tissue-specific ER stress and systemic metabolic imbalance, underscoring its pivotal role in maintaining whole-body homeostasis

A region in ASXL1 has recently been identified as a binding partner of the ET domain of BRD4 26 , prompting us to explore the mechanistic details and the functional significance of this interaction

KD has been found not only to reduce the frequency of seizures in patients with epilepsy [Keene, 2006] but also may help with Alzheimers disease [Ota et al ., 2019], improve motor functions and cognitive functions in Parkinsons disease [Phillips et al ., 2018], and support other neurodegenerative diseases [Zhao et al ., 2006]