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Berberine, an isoquinoline alkaloid from Coptis chinensis , disrupts Candida albicans cell-wall architecture by increasing surface exposure of -glucans and chitin, thereby weakening the barrier and heightening susceptibility to immune attack and antifungal agents (Shi et al., 2017

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142,222,225,385,386,387 It has also been demonstrated that the enzymes in glycolysis (e.g., GLUT4, HK1, GSK3B, and GAPDH), the enzymes (e.g., PDPR PDHA1, and PDHX) in carbohydrate metabolism, and most enzymes in ETC and ATP synthesis are assigned as ADP-ribose amino acid acceptor

1 Moreover, higher levels of renal nitrotyrosine, malondialdehyde (MDA), gp91 phox , p22 phox in 24-week-old SHR imply a potential involvement of oxidative stress in the maintenance of hypertension