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Disclosures: Lauren Rutt: Nothing to Disclose, Rebecca McCullough: Nothing to Disclose 1483 NALTREXONE USE IN PATIENTS WITH COMBINED METABOLIC AND ALCOHOL-ASSOCIATED LIVER DISEASE (METALD), PROPENSITY SCORE MATCHED STUDY Amir Hossein Gougol 1 Paul Kwo 2 C Pike 3 Saurabh Gombar 3 Gavin Hui 3 , 1 Stanford University, 2 Stanford University Medical Center, 3 Atropos Health Background: Naltrexone has demonstrated efficacy in management of alcohol use disorder

10.3390/ijms21197391 28 ChouA

After chloroquine inhibited mitochondrial autophagic flux, LC3B-II accumulated, LC3B-II/I elevated, and the levels of Pink1 and Parkin significantly reduced (Fig